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Sports supplements are a great way for women to improve their physique, unfortunately, most supplements focus on men. Researchers started to modify the testosterone molecule chemical structure in the 40s and these initial compounds were seen as steroidal. The first company that started developing cyclic quinolinones was Ligand Pharmaceuticals and these were the first compounds known as nonsteroidal selective androgen receptor modulators. For the past decade researchers managed to make lots of improvements when it comes to the oral bioavailability of these compounds. They also got to decrease just how much hepatic toxicity they have too, which is a very good thing.

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